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Wheeze
From Chewiki Archive - YouChew:
1% Funny, 99% Hot Gas
Notice: We are aware that many of the Chewiki’s images are still broken. We promise: we will try our best to fix it, but we don't guarantee that the fix will be trivial.
That strange little noise Mama Luigi makes after he says his catchphrase. However, it should be noted that Mama Luigi does not have asthma, but rather a lung condition where he has to wheeze everytime he says his catchphrase.